Ok..I read the article and still sit back and think wow. For >90% of a total synthesis Steven Ley’s group used a flow approach. The scheme below is telling and I will simply point you to a blog covering his impression (In the Pipeline – Derek Lowe). For the publication, you can find it here Angew. (Chem. Int. Ed. 2014)– CO-WORKERS is in bold on this one folks.