Mixing organic and aqueous phases in flow – moving forward fast

Enjoying the efforts of of Christopher Hone and his jflowchemistry blog. His latest article on catalyst, organic and liquid phase models for flow reaction chemistry was intriguing to say the least. There is a lot of interest in the ability to mix organic and aqueous phases – and then add reactive gas into the mix as it were. His description of Yap and co-workers at the National University of Singapore indicates that feasibility studies are ongoing to have a cleaner picture of what is controlling this sort of reaction (mass flow, heat transfer). What I enjoyed most is the subtleties of moving from a fixed bed or homogeneous catalysis into a design with the catalyst immobilized in the aqueous phase and work out the parameters — mixing, organic phase wetting, and finally introduction of gas. With the improvement and advancement of catalyst design — nanocatalyst — we may well see a number of new things being applied to flow design in the near future.

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Nice job Chris — keep em coming! Happy reading to the audience!